CASE REPORT |
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Year : 2010 | Volume
: 16
| Issue : 1 | Page : 46-48 |
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Mucin-secreting gastric adenocarcinoma with Rhabdoid areas
Sonal Sharma1, Richa Gupta1, Rajeev Sharma2, Mrinalini Kotru1
1 Department of Pathology, University College of Medical Sciences, Delhi, India 2 Specialist, Surgery, St Stephen's Hospital, Delhi, India
Correspondence Address:
Sonal Sharma Department of Pathology, University College of Medical Sciences, Shahdara, Delhi - 110 095 India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1319-3767.58769
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Rhabdoid tumor, first described in kidneys of infants and children, is an aggressive tumor that has been reported in several extrarenal locations. In this report, we describe the case of a 40-year-old patient with gastric adenocarcinoma composed of histologically well-differentiated glandular areas and focal rhabdoid zones. The rhabdoid component showed typical features such as abundant eosinophilic cytoplasm, eccentric nuclei, prominent nucleoli and intense focal positive immunohistochemical cytoplasmic reaction for vimentin. Recognition of the rhabdoid phenotype in gastrointestinal tract neoplasms is important because this feature is associated with poor prognosis and unresponsiveness to conventional therapy. |
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