Saudi Journal of Gastroenterology
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Year : 2013  |  Volume : 19  |  Issue : 6  |  Page : 245-251

Oral conditions associated with Hepatitis C virus infection


1 Department of Gastroenterology and Hepatology, Baqiyatallah University of Medical Sciences, Research Center for Gastroenterology and Liver Disease, Tehran, Iran
2 Department of Neurology, Marien Hospital Euskirchen, Lehrkrankenhaus der Uni-Bonn, Germany
3 Department of Oral and Maxillofacial Surgery, Tehran University of Medical Sciences, Tehran, Iran
4 Department of Medicine, Imperial College, Variety Wing Floor D, St Mary's Campus, Norfolk Place, London, United Kingdom

Correspondence Address:
Seyed-Moayed Alavian
Professor of Gastroenterology and Hepatology, Baqiyatallah Research Center for Gastroenterology and Liver Diseases, Ground Floor of Baqiyatallah Hospital, Mollasadra Avenue, Vanak Square
Iran
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1319-3767.121032

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Hepatitis C virus (HCV) infection in more than 170 million chronically infected patients with no developed preventive vaccine is a globally important issue. In addition to expected hepatic manifestations, a number of extrahepatic manifestations, such as mixed cryoglobulinemia, glomerulonephritis, polyarteritis nodosa, rashes, renal disease, neuropathy, and lymphoma, have been reported following HCV infection, which are believed to be influenced by the virus or the host immune response. HCV combination therapy with pegylated interferon and ribavirin might be associated with side effects as well. The association of HCV with special oral conditions has also been reported recurrently; the mechanism of most of which remains unclear. This article reviews the association of HCV infection with some of the oral conditions such as oral health, Sjogren's syndrome, lichen planus and oral cancer.


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