| Abstract|| |
Background/Aims: There is a high prevalence of depression and anxiety disorders among gastroenterological outpatients. Relatively few studies have been done on the help-seeking behavior among those who suffer from gastrointestinal symptoms with or without psychiatric disorders. We aimed to characterize the help-seeking behavior of gastroenterological outpatients and to evaluate if this behavior is linked to the presence of depression and anxiety. Patients and Methods: A cross-sectional study was carried out in gastroenterology clinics in four hospitals in Riyadh between February and September 2013. A self-administrated questionnaire was developed and administered to patients. Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder (GAD-7) questionnaires were used to diagnose depression and anxiety, respectively. Results: A total of 440 patients completed the study questionnaire. The average age was 36.0 ± 12.8 years and 69% of the patients were males. Complaints included abdominal pain (58%), heartburn (29%), diarrhea or constipation (25%), appetite or weight changes (22%), and nausea or vomiting (16%). Depression was diagnosed in 36%, while anxiety was diagnosed in 28% of the patients. The first intervention was use of medications (68%) and undergoing endoscopy (16%), while few patients initially used herbs or Islamic incantation (7.5%). This first intervention was done primarily (59%) in private sector hospitals rather than government sector hospitals (36%). The rates of depression and anxiety in our patients were higher among those who suffered from multiple complaints for longer durations and with less satisfaction with the offered services. Conclusion: Depression and anxiety are common comorbidities in gastroenterological outpatient population, especially those who have a chronic course of multiple gastrointestinal complaints.
Keywords: Anxiety, depression, gastroenterological, help-seeking behavior, psychiatric disorders, Saudi Arabia
|How to cite this article:|
Alosaimi FD, Al-sultan O, Alghamdi Q, Almohaimeed I, Alqannas S. Association of help-seeking behavior with depression and anxiety disorders among gastroenterological patients in Saudi Arabia. Saudi J Gastroenterol 2014;20:233-40
|How to cite this URL:|
Alosaimi FD, Al-sultan O, Alghamdi Q, Almohaimeed I, Alqannas S. Association of help-seeking behavior with depression and anxiety disorders among gastroenterological patients in Saudi Arabia. Saudi J Gastroenterol [serial online] 2014 [cited 2020 Jan 22];20:233-40. Available from: http://www.saudijgastro.com/text.asp?2014/20/4/233/136977
Illness behavior is the behavior undertaken by an individual who feels ill to relieve that experience or to better describe the meaning of the illness experience.  Therefore, those who experience physical or mental symptoms may seek help from the conventional healthcare system or use complementary or alternative medicine, while others may decide to dismiss the symptoms.  The illness behavior is the product of many complex factors including individual, healthcare system, and environmental characteristics.  Help-seeking behavior is considered an adaptive mode of coping with concerns or problems, whereas maladaptive coping style can lead to depression and other psychiatric disorders.  Several studies have described a number of factors that can influence an individual's help-seeking behavior, such as; gender, age, ethnicity, education, socioeconomic status, family structure, social networks, symptomatology and its perception, personality and coping appraisal, and access to healthcare systems. ,,
There is a high prevalence of depression and anxiety disorders among gastroenterological outpatients. ,, Several studies have examined the help-seeking behavior in patients with psychiatric diseases, particularly depression and anxiety. , However, relatively fewer studies have been done on the help-seeking behavior among those who suffer from gastrointestinal symptoms with  or without  psychiatric disorders. Data on help-seeking behavior among the Saudi population are scanty, old, and not disease specific.  Our null hypothesis was that gastroenterological outpatients equally use private and governmental sectors, and conventional and traditional therapies, and their help-seeking behavior is not affected by the concomitant presence of psychiatric disorders. The objective of the current study was to characterize help-seeking behavior among gastroenterological outpatients and to evaluate if this behavior is linked to the presence of depression or anxiety.
| Patients and Methods|| |
The current study was conducted among the outpatients attending gastroenterology clinic in one of the following four hospitals in Riyadh: King Khalid University Hospital (KKUH), King Fahad Medical city (KFMC), Dallah Hospital, and Dr. Sulaiman Al-Habib Arryan Hospital. All hospitals provide gastroenterology services to their patients. KKUH and KFMC hospitals are government hospitals, while Dallah and Dr. Sulaiman Al-Habib Arryan Hospitals are private hospitals. Both adult male and female patients above the age of 18 years were included. No exclusion was based on clinical diagnosis or duration of the disease.
A cross-sectional study was carried out between February and September 2013. The study obtained all required ethical approvals from the institutional review board at Faculty of Medicine at King Saud University, Riyadh, Saudi Arabia.
So far, no population-based, epidemiological survey of psychiatric disorders has been conducted in Saudi Arabia. However, previous clinical studies among Saudi patients estimated the prevalence of depression at 20-40% and anxiety at 24%. ,, We estimated that 384 patients are required to detect 30% prevalence of depression with 5% precision and 80% power. However, since the two groups were not assumed to be equal (non-depression was assumed double of depression), we estimated that 431 patients are required to detect 10% difference (e.g. 20% vs. 10%) of a given help-seeking characteristic between the two study groups at 95% confidence level and 80% power.
A self-administered questionnaire was developed and administered to all participants. It included three sections: Socio-demographic, help-seeking behavior, and validated tools that measure the presence of depression and anxiety. The first section included socio-demographic data such as age, gender, marital status, nationality, educational level, monthly income, occupation, residence, and type of housing. The second section included information about the gastrointestinal complaints (number, type, duration, awareness of diagnosis and underlying causes, associated distress and worry, impact on daily activities, and presence of other medical and psychiatric comorbidities) and the behavior following the development of symptoms (first intervention, type of healthcare facilities utilized, factors affecting the choice of a healthcare facility, satisfaction with services, and costs of diagnosis and treatment). The third section used the Arabic version of the nine-item Patient Health Questionnaire (PHQ-9) to assess the presence of depression and the seven-item Generalized Anxiety Disorder (GAD-7) questionnaire to assess the presence of anxiety. The content of the study questionnaire was validated by experts in gastroenterology and psychiatry to ensure the relevance and applicability of different questions. The questionnaire was then pilot tested on a small number of participants (n = 20) before widespread distribution. The wording and suggested answers were modified for some questions based on the feedback from the pilot sample.
Since it is almost impossible to get the roster of patients covered by each hospital, the questionnaire was distributed to patients attending the gastroenterology clinic at the time of the study, i.e. convenience sampling. The questionnaire was distributed just before or after the clinic visit. Informed written consent was obtained from all participants after explanation of the study objectives. The participation rate was 88% of all contacted patients (440/500).
Data were presented using frequencies and percentages for categorical data and mean and standard deviation (SD) for continuous data. Scores were calculated for PHQ-9 and GAD-7 with the maximum score 27 for PHQ-9 and 21 for GAD-7. As suggested earlier, those who got a score ≥10 on PHQ-9 were considered as having symptoms suggestive of depression,  while those who got a score ≥10 on GAD-7 were considered as having symptoms suggestive of anxiety.  Significant differences in the socio-demographic characteristics, complaints, and help-seeking behavior between those who had and those who did not have psychiatric disorders (depression or anxiety) were tested using Chi-square test or Fisher's exact test (as appropriate) for categorical data and Student's t-test for continuous data. All P values were two-tailed. P < 0.05 were considered significant. SPSS software (release 20.0, SPSS Inc., Chicago, IL, USA) was used for all statistical analyses.
| Results|| |
A total of 440 patients completed the study questionnaire. They were recruited from KKUH (155), Dallah hospital (149), KFMC (69), and Dr. Sulaiman Al-Habib Arryan Hospital (67). Socio-demographic characteristics of the patients are shown in [Table 1]. The average age was 36.0 ± 12.8 years, with approximately half of the patients aged between 25 and 44 years. About 70% of the patients were males and approximately two thirds were married. About 90% of the patients were Saudis. The majority (57%) of patients had college education or higher. The majority (56%) of patients had a monthly income of 10,000 SR or more. Approximately 40% of the patients were unemployed, while the remaining were mainly white-collar (47%) rather than blue-collar (13%) workers. About 90% of the patients were living in Riyadh and approximately two thirds owned a house.
|Table 1: Socio-demographic characteristics in relation to depression and anxiety disorders among outpatients attending gastroenterology clinic in four hospitals in Riyadh, Saudi Arabia (2013)|
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[Table 2] shows the gastrointestinal complaints among the study patients. The majority (58%) of patients had a single complaint, while about 41% had multiple complaints. The most commonly reported complaints were abdominal pain (58%), heart burn (29%), diarrhea or constipation (25%), appetite or weight changes (22%), and nausea or vomiting (16%). Almost 60% of patients suffered from the gastrointestinal complaints for a year or more. Half of the patients were unaware of the diagnosis of their symptoms and three quarters (74%) were unaware of the reasons behind them. The majority (76%) of patients reported average to significant distress due to their symptoms, but a much lower percentage (46%) were worried of having a serious disease behind their symptoms. Almost 60% of the patients reported average to significant negative impact of the symptoms on their daily activities. Approximately 28% of the patients reported being diagnosed with another medical disease and 6% of the patients reported being diagnosed with a psychiatric disease. Almost 20% of the patients reported the diagnosis of a serious disease in a family member.
|Table 2: Gastrointestinal complaints in relation to depression and anxiety disorders among outpatients attending gastroenterology clinic in four hospitals in Riyadh, Saudi Arabia (2013)|
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The help-seeking behavior of the study patients in response to the reported symptoms is shown in [Table 3]. The most common first interventions (diagnostic or therapeutic) were use of medications (68%) and undergoing endoscopy (16%), while very few patients initially used herbs or Islamic incantation (Roquia). This first intervention was done primarily (59%) in private hospitals and clinics more than in government hospitals and clinics (36%). Subsequent care was similarly provided by private (56%) and government (51%) hospitals and clinics. The choice of such hospitals and clinics was mainly due to hospital reputation (51%), presence of a health insurance (24%), previous positive experience (20%), and the presence of a relative working in these facilities (10%). The majority of the patients were totally (38%) or somewhat (34%) satisfied with the services they received in these hospitals. While the majority (63%) did not spend money, more than 20% spent 5000 SR or more on the diagnosis and treatment of their symptoms.
|Table 3: Help-seeking behavior in relation to depression and anxiety disorders among outpatients attending gastroenterology clinic in four hospitals in Riyadh, Saudi Arabia (2013)|
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Using the corresponding scales, depression symptoms were seen in 36% of the patients while anxiety symptoms were seen in 28% of the patients [Figure 1]. Those who had both symptoms formed 23%, while those who had either of them were 41%. [Table 1], [Table 2] and [Table 3] compare the association of depression and anxiety with the socio-demographic characteristics, complaints, and help-seeking behavior. Depression was significantly associated with female gender, lower education, and lower income. Depression also had a significant association with being divorced or widowed and having a Saudi nationality. Similarly, anxiety was significantly associated with middle age (25-44 years), female gender, and being divorced or widowed [Table 1]. Both depression and anxiety were associated with multiple complaints for longer durations. Anxiety was associated with pain and changes in appetite and weight, while depression was additionally associated with nausea, vomiting, diarrhea, and constipation. Both disorders had a high prevalence among those who reported significant degree of distress because of the symptoms or worries about their underlying causes. Their prevalence was also found to be higher among those with comorbidity including psychiatric diseases and those whose daily activities had been negatively impacted by their symptoms [Table 2]. Depression was seen more among patients recruited from Dr. Sulaiman Al-Habib Arryan Hospital, when the first intervention was Islamic incantation or surgery and when governmental hospitals were the place for first intervention. Both disorders had a higher prevalence among those who sought traditional healers. However, unlike anxiety, depression was higher in patients who sought multiple healthcare setting, irrespective of its type. Hospital reputation as a reason to choose the healthcare setting was the only reason associated with higher depression and anxiety. Lower levels of satisfaction with the obtained healthcare services and higher costs of diagnosis and treatment were associated with higher depression and anxiety [Table 3].
|Figure 1: Prevalence of depression and anxiety disorders among outpatients attending gastroenterology clinic in four hospitals in Riyadh, Saudi Arabia (2013)|
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| Discussion|| |
We are reporting the help-seeking behavior among gastroenterological outpatients recruited from four hospitals in Riyadh, Saudi Arabia. The first reaction of our patients to gastrointestinal symptoms was to use the conventional healthcare system. The use of unconventional therapies in the current study, including herbs or Islamic incantation, was much less than reported in other studies.  For example, it was estimated that 17% of diabetic patients attending diabetes clinic, 24% of asthmatic patients attending pulmonary clinic, and 32% of liver patients attending hepatology clinic were using herbs, compared with 3% in the current study. ,, This may be related to the chronic nature of the above patients compared with our patients (as the current clinic visit was the first or second visit in almost three-fourths of our patients), higher education of our patients, or effectiveness of the available medications in relieving gastrointestinal symptoms. Unlike several Western studies which showed that consultation rate and help seeking by men are consistently lower than that of women,  the majority of our patients were males. This may reflect the male predominance in primary health care utilization in Saudi Arabia due to logistic issues and choosy behavior of many women with regard to the gender and religion of the treating physician. 
As per Saudi labor policies, the employer has to provide the employee with free medical insurance, which probably makes the preference to private or governmental sectors driven mainly by accessibility rather than affordability. Private healthcare sector was preferred for the first visit after the onset of symptoms, probably due to the better reputation and easier access compared with governmental healthcare system, as seen in previous studies.  Additionally, sub-analysis of the current data (not shown) indicated a significant association between the presence of insurance and the use of private services, which can be explained by the private insurance provided by private employers. The loss of predominance of private healthcare in subsequent visits may be explained by the tendency to use free governmental services with multiple visits among those who paid for their first visit. The patient satisfaction with the utilized services in the current study was high and comparable to previous local studies that showed up to 80% satisfaction with primary care services. ,
Several studies have shown higher depression and anxiety rates among gastroenterological patients, and that these rates were proportional to the number of symptoms suffered. ,, The prevalence of depression (36%) and anxiety (28%) among our patients was generally comparable to that reported in previous local studies estimating their prevalence in primary care setting, as they were not estimated locally in gastroenterological patients. Using non-PHQ tool, local studies estimated depression at 39% among a representative sample of elderly Saudi patients with different complaints  and at 23% among the elderly patients attending primary care clinic in Jubail City, with higher rates among diabetics compared with non-diabetics (32% vs 16%).  Using the same tools as in the current study, depression was diagnosed in 20% while anxiety was diagnosed in 24% of Saudi primary care patients of all ages in Riyadh.  Internationally, using the same tools used in the current study, it was estimated that both depression and anxiety were affecting approximately 19% of the gastroenterological patients attending primary care clinics in the USA.  The lower rate observed in the latter study compared with our study may be explained by their higher cut-off point (≥15 vs. >15) used to define both depression and anxiety. Depression and/or anxiety in the current study were associated with a personal profile, including gender, marital status, income, and education, similar to that reported nationally and internationally. ,,
Help-seeking behavior in our patients was confounded by the presence of depression and anxiety, as suggested elsewhere.  For example, the rates of depression and anxiety in our patients were higher among those who suffered from multiple complaints for longer duration with less satisfaction with the offered services. Similarly, in a large sample of German patients with functional gastrointestinal disorders, the presence of psychiatric disorders including depression, as well as the duration and severity of the symptoms were among the independent predictors for the frequency of physician consultations.  Functional gastrointestinal symptoms may overwhelm the gastroenterology clinic with additional visits that otherwise need psychiatric management. This generated calls to incorporate a mental health professional as part of the multidisciplinary team in the gastroenterology clinic. 
The current study has many advantages: Bridging local knowledge gap in help-seeking behavior, surveying a sufficiently large number of patients from both private and governmental sectors, and studying the interaction between gastrointestinal and psychological complaints. Nevertheless, we acknowledge a number of limitations. Being a convenience sample, the results should be generalized with caution and should not be regarded as representative to Saudi gastroenterology patients. Lack of control group impeded our ability to distinguish the help-seeking behavior of gastroenterology outpatients with that of outpatients of other specialities. Being a self-reported study, the possibility of recall bias cannot be excluded. Finally, using self-rated scales to diagnose depression and anxiety may be less accurate compared with diagnostic interview conducted by a healthcare professional. However, these scales are well validated and easier to implement in busy gastroenterology clinics.
In conclusion, we are reporting largely on the conventional help-seeking behavior among gastroenterological outpatients in Saudi Arabia, with a minor role for unconventional therapies. Help-seeking behavior among these patients was confounded by the presence of relatively a high proportion of depression and anxiety. Further research may be needed to assess whether incorporating a mental health professional as a part of a multidisciplinary team in gastroenterology clinic may reduce the number of visits and shorten the course in patients with gastrointestinal complaints.
| Acknowledgments|| |
The authors would like to acknowledge the support from College of Medicine Research Center, Deanship of Scientific Research, King Saud University. Moreover, many thanks for our collaborators in King Khalid University Hospital, King Fahad Medical city, Dallah Hospital, and Dr. Sulaiman Al-Habib Arryan Hospital. Furthermore, the authors would like to express their gratitude to Dr. Aiman El-Saed (Asst. Professor of Epidemiology and Biostatistics) for his help in data analysis.
| References|| |
|1.||McQueen DV. Illness and sick-role behavior. Encyclopedia of public health. In: Breslow L, editor. Vol. 2. New York, USA: Gale Group; 2002. Available from: http://www.Enotes.Com/topics/illness-sick-role-behavior [Last accessed in 2013 Dec 27]. |
|2.||Mechanic D. Sociological dimensions of illness behavior. Soc Sci Med 1995;41:1207-16. |
|3.||Fallon BJ, Bowles TV. Family functioning and adolescent help-seeking behavior. Fam Relat 2001;50:239-45. |
|4.||West CM, Kantor GK, Jasinski JL. Sociodemographic predictors and cultural barriers to help-seeking behavior by latina and anglo american battered women. Violence Vict 1998;13:361-75. |
|5.||Shaw C. A review of the psychosocial predictors of help-seeking behaviour and impact on quality of life in people with urinary incontinence. J Clin Nurs 2001;10:15-24. |
|6.||Möller-Leimkühler AM. Barriers to help-seeking by men: A review of sociocultural and clinical literature with particular reference to depression. J Affect Disord 2002;71:1-9. |
|7.||Bener A, Ghuloum S, Al-Hamaq AO, Dafeeah EE. Association between psychological distress and gastrointestinal symptoms in diabetes mellitus. World J Diabetes 2012;3:123-9. |
|8.||Mussell M, Kroenke K, Spitzer RL, Williams JB, Herzog W, Lowe B. Gastrointestinal symptoms in primary care: Prevalence and association with depression and anxiety. J Psychosom Res 2008;64:605-12. |
|9.||Haug TT, Mykletun A, Dahl AA. Are anxiety and depression related to gastrointestinal symptoms in the general population? Scand J Gastroenterol 2002;37:294-8. |
|10.||Kwong K, Chung H, Cheal K, Chou JC, Chen T. Disability beliefs and help-seeking behavior of depressed chinese-american patients in a primary care setting. J Soc Work Disabil Rehabil 2012;11:81-99. |
|11.||Zinzow HM, Brooks J, Stern EB. Driving-related anxiety in recently deployed service members: Cues, mental health correlates, and help-seeking behavior. Mil Med 2013;178:e357-61. |
|12.||Herschbach P, Henrich G, von Rad M. Psychological factors in functional gastrointestinal disorders: Characteristics of the disorder or of the illness behavior? Psychosom Med 1999;61:148-53. |
|13.||Ringstrom G, Abrahamsson H, Strid H, Simren M. Why do subjects with irritable bowel syndrome seek health care for their symptoms? Scand J Gastroenterol 2007;42:1194-203. |
|14.||Al-Shammari SA. Help-seeking behavior of adults with health problems in Saudi Arabia. Fam Pract Res J 1992;12:75-82. |
|15.||Al-Shammari SA, Al-Subaie A. Prevalence and correlates of depression among saudi elderly. Int J Geriatr Psychiatry 1999;14:739-47. |
|16.||Shehatah A, Rabie MA, Al-Shahry A. Prevalence and correlates of depressive disorders in elderly with type 2 diabetes in primary health care settings. J Affect Disord 2010;123:197-201. |
|17.||Becker S, Al Zaid K, Al Faris E. Screening for somatization and depression in Saudi Arabia: A validation study of the phq in primary care. Int J Psychiatry Med 2002;32:271-83. |
|18.||Gilbody S, Richards D, Brealey S, Hewitt C. Screening for depression in medical settings with the patient health questionnaire (phq): A diagnostic meta-analysis. J Gen Intern Med 2007;22:1596-602. |
|19.||Spitzer RL, Kroenke K, Williams JB, Lowe B. A brief measure for assessing generalized anxiety disorder: The gad-7. Arch Intern Med 2006;166:1092-7. |
|20.||Al Moamary MS. Unconventional therapy use among asthma patients in a tertiary care center in riyadh, Saudi Arabia. Ann Thorac Med 2008;3:48-51. |
|21.||Al-Rowais NA. Herbal medicine in the treatment of diabetes mellitus. Saudi Med J 2002;23:1327-31. |
|22.||Al-Zahim AA, Al-Malki NY, Al-Abdulkarim FM, Al-Sofayan SA, Abunab HA, Abdo AA. Use of alternative medicine by Saudi liver disease patients attending a tertiary care center: Prevalence and attitudes. Saudi J Gastroenterol 2013;19:75-80. |
|23.||Addis ME, Mahalik JR. Men, masculinity, and the contexts of help seeking. Am Psychol 2003;58:5-14. |
|24.||Saeed AA, Mohamed BA. Patients′ perspective on factors affecting utilization of primary health care centers in Riyadh, Saudi Arabia. Saudi Med J 2002;23:1237-42. |
|25.||Al-Doghaither AH, Abdelrhman BM, Saeed AA, Magzoub ME. Factors influencing patient choice of hospitals in Riyadh, Saudi Arabia. J R Soc Promot Health 2003;123:105-9. |
|26.||Al-Sakkak MA, Al-Nowaiser NA, Al-Khashan HI, Al-Abdrabulnabi AA, Jaber RM. Patient satisfaction with primary health care services in riyadh. Saudi Med J 2008;29:432-6. |
|27.||Mahfouz AA, Al-Sharif AI, El-Gama MN, Kisha AH. Primary health care services utilization and satisfaction among the elderly in Asir Region, Saudi Arabia. East Mediterr Health J 2004;10:365-71. |
|28.||Lejtzen N, Sundquist J, Sundquist K, Li X. Depression and anxiety in Swedish primary health care: Prevalence, incidence, and risk factors. Eur Arch Psychiatry Clin Neurosci 2013 [Epub ahead of print]. |
|29.||Mikocka-Walus A, Turnbull D, Andrews JM, Moulding N, Wilson I, Holtmann G. Psychogastroenterology: A call for psychological input in Australian gastroenterology clinics. Intern Med J 2009;39:127-30. |
Dr. Fahad D Alosaimi
Department of Psychiatry, King Saud University, PO Box 7805, Riyadh - 11472
Kingdom of Saudi Arabia
Source of Support: None, Conflict of Interest: None
[Table 1], [Table 2], [Table 3]