Saudi Journal of Gastroenterology
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Year : 2015  |  Volume : 21  |  Issue : 1  |  Page : 11-17

Surgical Treatment for Hepatocellular Carcinoma


1 Department of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia; Section of Hepatopancreatobilairy and Transplant, Transplant, McGill University, Montreal, Canada
2 Section of Hepatopancreatobilairy and Transplant, Transplant, McGill University, Montreal, Canada; Department of Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
3 Department of Surgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
4 Department of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia; Department of Oncology, McGill University, Montreal, Canada

Correspondence Address:
Mazen M Hassanain
Assistant Professor of Surgery and Consultant HPB and Transplant Surgery, Department of Surgery, College of Medicine, Scientific Director Liver Disease Research Centre, King Saud University, P.O.Box 25179, Riyadh, 11466

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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1319-3767.151216

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Hepatocellular carcinoma (HCC) is an epithelial tumor derived from hepatocytes; it accounts for 80% of all primary liver cancers and ranks globally as the fourth leading cause of cancer-related deaths. HCC treatment is a multidisciplinary and a multimodal task, with surgery in the form of liver resection and liver transplantation (LT) representing the only potentially curative modality. However, there are variable opinions and discussions about applying these surgical options and using other supporting treatments. This article is a narrative review that includes articles published from 1984 to 2013 located by searching scientific databases such as PubMed, SCOPUS, and Elsevier, with the main keyword of hepatocellular carcinoma in addition to other keywords such as liver transplantation, liver resection, transarterial chemoembolization, portal vein embolization, bridging therapy, and downstaging. In this review, we focus mainly on the surgical treatment options offered for HCC, in order to illustrate the current relevant data available in the literature to help in applying these surgical options and to use other supporting treatment modalities when appropriate.


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