Saudi Journal of Gastroenterology

CASE REPORT
Year
: 2016  |  Volume : 22  |  Issue : 6  |  Page : 461--464

Gluten-Free hepatomiracle in “celiac hepatitis”: A case highlighting the rare occurrence of nutrition-induced near total reversal of advanced steatohepatitis and cirrhosis


Kavita Gaur1, Puja Sakhuja1, Amarender S Puri2, Kaushik Majumdar1 
1 Department of Pathology, GB Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India
2 Department of Gastroenterology, GB Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi, India

Correspondence Address:
Puja Sakhuja
Department of Pathology, GB Pant Institute of Postgraduate Medical Education and Research (GIPMER), New Delhi
India

Regression of hepatic fibrosis is increasingly becoming a reality, both in clinical as well as experimental models. Reversal or near-total regression of marked liver steatohepatitis and fibrosis, however, remains a rare event. We report the case of a 20-year-old female presenting with diarrhea due to celiac disease and biopsy proven cirrhosis with portal hypertension who had a remarkable clinical improvement in response to a gluten free diet (GFD). A follow-up liver biopsy 9 months after the initiation of GFD revealed a remarkable regression of both fibrosis as well as steatosis. Villous atrophy, as seen in patients with celiac disease, could lead to a deprivation of trophic factors leading to liver injury and subsequent cirrhosis. A gluten-free dietary regimen can produce a reversal of fibrosis leading to the amelioration of symptoms associated even with advanced liver disease.


How to cite this article:
Gaur K, Sakhuja P, Puri AS, Majumdar K. Gluten-Free hepatomiracle in “celiac hepatitis”: A case highlighting the rare occurrence of nutrition-induced near total reversal of advanced steatohepatitis and cirrhosis.Saudi J Gastroenterol 2016;22:461-464


How to cite this URL:
Gaur K, Sakhuja P, Puri AS, Majumdar K. Gluten-Free hepatomiracle in “celiac hepatitis”: A case highlighting the rare occurrence of nutrition-induced near total reversal of advanced steatohepatitis and cirrhosis. Saudi J Gastroenterol [serial online] 2016 [cited 2019 Aug 19 ];22:461-464
Available from: http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2016;volume=22;issue=6;spage=461;epage=464;aulast=Gaur;type=0