Saudi Journal of Gastroenterology

SYSTEMATIC REVIEW/META ANALYSIS
Year
: 2019  |  Volume : 25  |  Issue : 1  |  Page : 14--19

A meta-analysis of early oral refeeding and quickly increased diet for patients with mild acute pancreatitis


Jiran Zhang1, Sha Zhu2, Dingyu Tan1, Aiwen Ma1, Yan Yang1, Jiyang Xu1 
1 Department of Emergency, Clinical Medical College of Yangzhou University, Subei People's Hospital, Yangzhou 225001, Jiangsu Province, China
2 Department of Operating Room, Clinical Medical College of Yangzhou University, Subei People's Hospital, Yangzhou 225001, Jiangsu Province, China

Correspondence Address:
Prof. Jiyang Xu
Clinical Medical College of Yangzhou University, Subei People's Hospital, Nantong West Road, 98Yangzhou 225001, Jiangsu Province
China

Background/Aim: The objective of the study is to clarify whether early oral refeeding (EORF) and quickly increasing diet (QID) are of benefit to patients with mild acute pancreatitis compared with a traditional oral refeeding strategy. Materials and Methods: Studies were searched in PubMed, Cochrane library, ScienceDirect, SpringerLink, China Biology Medicine disc and Embase. A meta-analysis was then performed, using relapse of abdominal pain, nausea/vomiting, and length of hospital stay (LOHS) as the evaluation indices. Results: Eight trials met the inclusion criteria. For the oral refeeding time group, EORF could significantly decrease the LOHS (mean deviation [MD] −1.97; 95% confidence interval (CI) −3.32 to −0.62;P = 0.004), and there was no significant difference for relapse of abdominal pain (relative risk [RR] 1.17; 95% CI 0.69–2.00;P = 0.56) or nausea/vomiting (RR 1.30; 95% CI 0.19–8.82;P = 0.79) when compared with conventional oral refeeding. For the oral refeeding material group, there was no significant difference for relapse of abdominal pain (RR 0.86; 95% CI 0.53–1.40;P = 0.54), nausea/vomiting (risk difference −0.01; 95% CI −0.19–0.18;P = 0.94), or LOHS (MD −0.88; 95% CI −2.24–0.48;P = 0.20) between the QID and stepwise increasing diet groups. Conclusion: Pure EORF or QID caused no damage to patients with mild acute pancreatitis, and EORF could significantly decrease the LOHS.


How to cite this article:
Zhang J, Zhu S, Tan D, Ma A, Yang Y, Xu J. A meta-analysis of early oral refeeding and quickly increased diet for patients with mild acute pancreatitis.Saudi J Gastroenterol 2019;25:14-19


How to cite this URL:
Zhang J, Zhu S, Tan D, Ma A, Yang Y, Xu J. A meta-analysis of early oral refeeding and quickly increased diet for patients with mild acute pancreatitis. Saudi J Gastroenterol [serial online] 2019 [cited 2019 Jul 16 ];25:14-19
Available from: http://www.saudijgastro.com/article.asp?issn=1319-3767;year=2019;volume=25;issue=1;spage=14;epage=19;aulast=Zhang;type=0