Saudi Journal of Gastroenterology
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Year : 1997  |  Volume : 3  |  Issue : 3  |  Page : 121-124

Pattern of helicobacter pylori sensitivity to various antimicrobial agents


1 Department of Medicine, College of Medicine & KKUH, P.O. Box 2925, Riyadh 11461, Saudi Arabia
2 Department of Microbiology, College of Medicine & KKUH, P.O. Box 2925, Riyadh 11461, Saudi Arabia
3 Department of Pharmacy, College of Medicine & KKUH, P.O. Box 2925, Riyadh 11461, Saudi Arabia

Correspondence Address:
Saleh Mohsin Al Amri
Associate Professor & Consultant Physician, Gastroenterology Division (59), College of Medicine & KKUH, P.O. Box 2925, Riyadh 11461
Saudi Arabia
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Source of Support: None, Conflict of Interest: None


PMID: 19864788

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To evaluate the pattern of Helicobacter pylori ( H. pylori ) susceptibility to different antimicrobial agents, we prospectively studied 45 H. pylori isolates by disc diffusion method. These isolates were obtained from patients aged between 16-75 years, of both sexes who had no prior history of metronidazole ingestion. A total of 45 patients were included, of which 36 were males with a mean age of 42.9 years and nine females with a mean age of 36.4 years, 62% of patients were Saudis. Almost all the H. pylori isolates were susceptible to clarithromycin, penicillin, erythromycin, ampicillin, tetracycline, clindamycin and cephradine. However, 64.4% of the isolates were resistant to metronidazole. No significant difference was found either in susceptibility of isolates from Saudi, non-Saudi or male and female patients.


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