Saudi Journal of Gastroenterology
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Year : 2004  |  Volume : 10  |  Issue : 3  |  Page : 144-149

Outcome of pancreaticoduodenectomy: Comparing the classic whipple with pyloric preservation

Guilan University of Medical Sciences, Rasht, Iran

Correspondence Address:
Mohammed Reza Kohsari
Department of General Surgery, Razi Hospital, P 0 Box 41448-95655, Rasht
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Source of Support: None, Conflict of Interest: None

PMID: 19861838

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Background: The majority of patients presenting with periampullary neoplasms are operative candidates and are treated surgically. Aim of the study: To assess the complications, morbidity, mortality and 2-year survival rates, and safety of pancreaticoduodenectomy for periampullary carcinomas in a non-oncology surgical set-up. Patients and methods: Records of 23 patients underwent pancreaticoduodenectomy for periampullary cancers between July 1995 and April 2001 in Guilan, Iran, were reviewed. Results: Among 23 consecutive patients who underwent pancreaticoduodenectomy, 16 were men and 7 were women, and the mean age was 58 +/-10.2years. All the patients had a malignant neoplasm. Mean operative time was 7.3 hours. The surgical procedure was pylorus-preserving pancreaticoduodenectomy (PPPD) in 65%. The median intraoperative blood loss was 625 ml and no transfusion was required. There was no intraoperative mortality, and the overall 30-day postoperative mortality rate was 4.5%. Delayed gastric emptying was the most common postoperative complication. The 2-year survival rates for periampullary cancers were 93% in PPPD and 62.5% in classic Whipple procedure. Conclusion: Pancreaticoduodenectomy for periampullary tumors remains a formidable procedure in our set-up. It can be performed safely with low mortality and morbidity rates

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