Saudi Journal of Gastroenterology

ARTICLES
Year
: 2004  |  Volume : 10  |  Issue : 1  |  Page : 22--27

Ulcerative colitis: Al-gassim experience


Qais Qutub Contractor1, Tasneern Qais Contractor2, Imran Ul Haque3, El Mahdi El Badawi El Mahdi1 
1 Department of Medicine, King Fahad Specialist Hospital, Buraidah, Al-Gassim, Saudi Arabia
2 Department of Surgery, King Fahad Specialist Hospital, Buraidah, Al-Gassim, Saudi Arabia
3 Department of Laboratory Medicine, King Fahad Specialist Hospital, Buraidah, Al-Gassim, Saudi Arabia

Correspondence Address:
Qais Qutub Contractor
King Fahad Specialist Hospital, P 0 Box 2290, Buraidah, Al-Gassim
Saudi Arabia

Background: Ulcerative colitis (UC) is being reported more frequently among the Arabs. Information on the clinical severity, endoscopic and histological grading is scanty. Aim: To assess the severity of the disease and its response to therapy in patients referred to a tertiary care referral centre in Gassim region, Kingdom of Saudi Arabia (KSA). Patients and Method: Hospital records of thirty-four patients found to have UC from 1990-2002 were analyzed. The study included clinical severity, endoscopical and histological assessment, response to therapy and frequency of complications. Results: There were 21 males and 13 females with median age 35 (range: 18-76) years. The disease was clinically mild in seven patients (21%), moderate in 11 (32%) and severe in 16 (47%). Endoscopically UC was graded as 2 in three patients (9%), 3 in 21 patients (59%) and 4 in ten patients (29%). Histologically UC was mild to moderate in 11 patients (32%) and severe in 23 (68%). Extent of UC was total in nine patients (26%), up to transverse colon in six (18%), splenic flexure in 14 (41%), rectosigmoid region in four (12%) and only up to the rectum in one (3%). Twenty-nine patients (85%) were treated with salazopyrine and five patients (15%); (two of them were hypersensitive to salazopyrine) received 5­aminosalicylic acid. Proctocolectomy was performed in two with a focus of malignancy. No patient died during the median follow-up period of 48 months (range: 4 months to 12 years). Conclusion: Ulcerative colitis presented with varying severity, more frequently in males in the population studied. Most of the patients responded to salazopyrine and surgery was necessary when malignancy was detected


How to cite this article:
Contractor QQ, Contractor TQ, Ul Haque I, El Mahdi EE. Ulcerative colitis: Al-gassim experience.Saudi J Gastroenterol 2004;10:22-27


How to cite this URL:
Contractor QQ, Contractor TQ, Ul Haque I, El Mahdi EE. Ulcerative colitis: Al-gassim experience. Saudi J Gastroenterol [serial online] 2004 [cited 2020 Dec 6 ];10:22-27
Available from: https://www.saudijgastro.com/article.asp?issn=1319-3767;year=2004;volume=10;issue=1;spage=22;epage=27;aulast=Contractor;type=0