Saudi Journal of Gastroenterology

ARTICLES
Year
: 2004  |  Volume : 10  |  Issue : 2  |  Page : 78--85

Does helicobacter pylori infection in chronic renal failure increase the risk of gastroduodenal lesions? A prospective study


Ibrahim Saeed Abdulrahman1, Samir Habib Al-Mueilo1, Mona Hassan Ismail1, Mohamed Ismail Yasawy1, Fahad Nasser Al-Qahtani2, Abdulaziz Abdulatif Al-Qorain1 
1 Department of Medicine, King Fahad Hospital of the University, P 0 Box 40032, Al Khobar, 31952, Saudi Arabia
2 Department of Radiology, King Fahad Hospital of the University, P 0 Box 40032, Al Khobar, 31952, Saudi Arabia

Correspondence Address:
Ibrahim Saeed Abdulrahman
King Fahad Hospital of the University, P 0 Box 40032, Al Khobar, 31952
Saudi Arabia

Background: Helicobacter pylori (H.pylori) plays an important role in gastroduodenal disease. However, there are few data concerning the epidemiology of H.pylori in patients with chronic renal failure and on hemodialysis (HD) treatment. Aim of the study: This study is aimed to determine the epidemiology of H.pylori infection in patients with end stage renal disease (ESRD) on Hemodialysis (HD). Patients and Methods: Ninety­six patients with dyspeptic complaints were included in the study. They were divided into two groups; group one consisted of 46 patients with ESRD on HD and group two (control) of 50 patients without renal disease. All patients were subjected to upper gastrointestinal endoscopies, and gastric biopsies were obtained for histological evidence of H. pylori infection. Results: The mean age of both groups was similar. The prevalence of H.pylori among the two groups was not significantly different (45.7%Vs48%=p>0.05). The prevalence of duodenal ulcers was significantly higher in H.pylori positive than in H.pylori negative ESRD patients (p<0.05). GERD was significantly lower in H.pylori positive patients in both groups (p<0.001 and p<0.01 respectively). Conclusion: This study showed a similar prevalence of H.pylori infection in both groups. H.pylori infection in patients with ESRD is probably associated with increased risk of gastroduodenal lesions


How to cite this article:
Abdulrahman IS, Al-Mueilo SH, Ismail MH, Yasawy MI, Al-Qahtani FN, Al-Qorain AA. Does helicobacter pylori infection in chronic renal failure increase the risk of gastroduodenal lesions? A prospective study.Saudi J Gastroenterol 2004;10:78-85


How to cite this URL:
Abdulrahman IS, Al-Mueilo SH, Ismail MH, Yasawy MI, Al-Qahtani FN, Al-Qorain AA. Does helicobacter pylori infection in chronic renal failure increase the risk of gastroduodenal lesions? A prospective study. Saudi J Gastroenterol [serial online] 2004 [cited 2020 Oct 24 ];10:78-85
Available from: https://www.saudijgastro.com/article.asp?issn=1319-3767;year=2004;volume=10;issue=2;spage=78;epage=85;aulast=Abdulrahman;type=0