Saudi Journal of Gastroenterology

ORIGINAL ARTICLE
Year
: 2007  |  Volume : 13  |  Issue : 1  |  Page : 21--24

Radiological response in Saudi patients undergoing transarterial chemoembolization for hepatocellular carcinoma


Turki Al Fuhaid1, Majid Al Madi2, Huda Al Abdul Kareem3, Manal Al Dukhayil3, Ayman A Abdo3 
1 Department of Radiology, King Khalid University Hospital, Riyadh, Saudi Arabia
2 Gastroenterology Unit, Department of Medicine, McGill University, Montreal, Canada
3 Department of Medicine, King Khalid University Hospital, Riyadh, Saudi Arabia

Correspondence Address:
Ayman A Abdo
College of Medicine, P.O. Box 2925 (59), Riyadh 11461
Saudi Arabia

Background: Hepatocellular carcinoma (HCC) is the second commonest cancer affecting males and the eighth most common one affecting females in Saudi Arabia. Transarterial chemoembolization (TACE) is currently considered the first line therapy for multifocal HCC in selected patients. Objective: To evaluate HCC response to TACE based on triphasic computerized tomography (CT) of the liver obtained 6 weeks after the procedure. Materials and Methods: A retrospective chart review of 15 patients who underwent TACE in King Khalid University Hospital for unresectable HCC. Patients were staged according to the Child-Pugh, Okuda, and CLIP scoring systems. The first triphasic CT of the liver after TACE was evaluated for Lipiodol uptake and interval change in tumor burden. Results: The mean age was 63 years (40-82), 10 were males (66.7%), and five were females. About 11 patients had cirrhosis (73.3%). Eight patients (53.3%) were Child-Pugh class A while seven (46.7%) were Child-Pugh class B. One patient died and two were lost to follow up. Four patients had a complete response to TACE (26.7%), two had a partial response (13.3%), five showed no change (33.3%) and none showed progression of disease. Tumoral Lipiodol uptake in five patients was >75% (33.3%), in two 75-50% (13.3%) while in four patients it was <50% (26.7%). Conclusion: Our results show that TACE is an effective method of reducing the tumor burden in selected patients with unresectable HCC.


How to cite this article:
Al Fuhaid T, Al Madi M, Al Abdul Kareem H, Al Dukhayil M, Abdo AA. Radiological response in Saudi patients undergoing transarterial chemoembolization for hepatocellular carcinoma.Saudi J Gastroenterol 2007;13:21-24


How to cite this URL:
Al Fuhaid T, Al Madi M, Al Abdul Kareem H, Al Dukhayil M, Abdo AA. Radiological response in Saudi patients undergoing transarterial chemoembolization for hepatocellular carcinoma. Saudi J Gastroenterol [serial online] 2007 [cited 2021 Nov 27 ];13:21-24
Available from: https://www.saudijgastro.com/article.asp?issn=1319-3767;year=2007;volume=13;issue=1;spage=21;epage=24;aulast=Al;type=0