Saudi Journal of Gastroenterology

REVIEW ARTICLE
Year
: 2014  |  Volume : 20  |  Issue : 5  |  Page : 279--287

Ascites and spontaneous bacterial peritonitis: Recommendations from two United States centers


Vinay Sundaram1, Vignan Manne1, Abdullah MS Al-Osaimi2 
1 Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA
2 Department of Medicine, Division of Hepatology, Temple University Health System, Philadelphia, Pennsylvania, USA

Correspondence Address:
Dr. Abdullah MS Al-Osaimi
Associate Professor of Medicine and Surgery, Division Chief of Hepatology, Medical Director of Liver Transplantation, Temple University Health System, 3440 N. Broad Street, Kresge Building West, Room 216, Philadelphia, Pennsylvania - 19103
USA

Cirrhosis affects millions of people throughout the world. Two of the most serious complications of liver cirrhosis are ascites and spontaneous bacterial peritonitis (SBP). The development of ascites is related to the severity of portal hypertension and is an indicator of increased mortality. Although sodium restriction and diuretic therapy have proven effective, some patients may not respond appropriately or develop adverse reactions to diuretic therapy. In such cases, interventions such as transjugular intrahepatic portosystemic shunt (TIPS) placement are warranted. SBP is a complication of ascites that confers a very high mortality rate. Recognition and prompt treatment of this condition is essential to prevent serious morbidity and mortality. Initiation of prophylaxis in SBP remains controversial. Given the burden of liver cirrhosis on the health care system, ascites and SBP will continue to provide challenges for the primary care provider, hospitalist, internist, and gastroenterologist alike.


How to cite this article:
Sundaram V, Manne V, Al-Osaimi AM. Ascites and spontaneous bacterial peritonitis: Recommendations from two United States centers.Saudi J Gastroenterol 2014;20:279-287


How to cite this URL:
Sundaram V, Manne V, Al-Osaimi AM. Ascites and spontaneous bacterial peritonitis: Recommendations from two United States centers. Saudi J Gastroenterol [serial online] 2014 [cited 2021 Nov 27 ];20:279-287
Available from: https://www.saudijgastro.com/article.asp?issn=1319-3767;year=2014;volume=20;issue=5;spage=279;epage=287;aulast=Sundaram;type=0