Saudi Journal of Gastroenterology
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   2004| May-August  | Volume 10 | Issue 2  
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A typical adult celiac disease: Report of cases and review of the literature
Mohamed Ismail Yasawy, Abdulaziz Abdulatif Al-Quorain, Dalal Mohammed Tamimi
May-August 2004, 10(2):99-102
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Bilateral paravertebral block in advanced schistosomal liver disease: A prospective study
Haitham Ahmed Abou Zeid, Abdul Mohsen Abdulah Al-Ghamdi, Maha Sid-Ahmed Abdel-Hadi, Hazem Mohamed Zakaria, Abdel Aziz Abdulatif Al-Quorain, Maisa Noureldin Shawkey
May-August 2004, 10(2):67-77
Background: Surgery in patients with schistosomal liver disease is usually associated with high risks of morbidity and mortality. Bilateral paravertebral block (BPVB) has been advocated as a useful technique for ventral abdominal hernias' repairs. Aim of the study: To compare the efficacy of BPVB with general anesthesia (GA) for anterior abdominal wall hernias in advanced schistosomal liver disease patients. Patients and Methods: Sixty patients were randomly allocated into two groups to receive either GA or BPVB. Variables were hospital stay, hemodynamic stability, postoperative nausea and vomiting (PONY), postoperative pain measured on a visual analogue scale (VAS) with assessment of the hepatic cell integrity using glutathione S transferase alpha (GSTA) and other liver enzymes. Results: The main significant finding was an apparently significant shorter length of hospital stay following BPVB as compared with GA in patients (P < 0.005). Conclusions: BPVB was superior to GA following abdominal ventral hernia repair in schistosomal liver fibrosis patients
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Alvarado score as an admission criterion for suspected appendicitis in adults
Hamad Hadi Al Qahtani, Abdulmajeed Abdulhameed Muhammad
May-August 2004, 10(2):86-91
Background.- Acute appendicitis is a common surgical problem. Aim of the Study: To assess Alvarado score as an admission criterion for adult patients with suspected appendicitis in order to decrease unnecessary admissions to surgical wards. Patients and Methods: A prospective study of consecutive patients attending the Emergency Department (ED) of Riyadh Medical Complex with suspected appendicitis. The patients were managed according to the algorithm of the study protocol and discharged after clinical improvement either from ED or from the ward. They were followed by telephone 2-3 days later. Alvarado score was obtained in the ED in all patients. Results: The study included 211 patients, 60 patients were observed in ED and discharged, 151 patients were admitted and 137 of them were operated with a negative rate of 12.5%. The remaining 14 patients were observed and discharged. No patients with a score of 4 or less had appendicitis. Conclusion: Though the diagnosis of acute appendicitis remains mainly clinical, Alvarado score can be recommended as a helpful tool for the admission criteria and further management in order to reduce unnecessary admissions and to reduce the morbidity and mortality of acute appendicitis
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Concepts in leptin and liver disease
Reda Mohammed El-Badawy, Abdullah Saeed Al-Ghamdi, Ibrahim Abdulkarim Al-Mofleh
May-August 2004, 10(2):57-66
Leptin is a cytokine l6kd peptide hormone. Its crucial role is regulation of appetite and the body fat mass mainly through action on the hypothalamus. It is produced mainly in adipocytes of white fat, as well as from other tissues e.g. placenta, skeletal muscles, fundus of the stomach and activated hepatic stellate cell (HSC) and recently reported that leptin is produced from B cell of islands of the pancreas. The gene responsible for production is present on chromosome 7 called obse gene (ob/gene). Leptin receptors (OB-R) were present in two forms short (OB-Ra or OB-RS) and long one (OB-Rb or OB-RI). The main action of leptin depends on long form (OB-Rl), where very little evidence is available implicating a role for the short form in the action of leptin. One of the unconventional areas in which leptin is now receiving great attention is liver diseases as several published studies indicate that circulating leptin level are increased in cirrhosis, hepatitis C virus (HCV) and non-alcoholic steatohepatitis (NASH)
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Does helicobacter pylori infection in chronic renal failure increase the risk of gastroduodenal lesions? A prospective study
Ibrahim Saeed Abdulrahman, Samir Habib Al-Mueilo, Mona Hassan Ismail, Mohamed Ismail Yasawy, Fahad Nasser Al-Qahtani, Abdulaziz Abdulatif Al-Qorain
May-August 2004, 10(2):78-85
Background: Helicobacter pylori (H.pylori) plays an important role in gastroduodenal disease. However, there are few data concerning the epidemiology of H.pylori in patients with chronic renal failure and on hemodialysis (HD) treatment. Aim of the study: This study is aimed to determine the epidemiology of H.pylori infection in patients with end stage renal disease (ESRD) on Hemodialysis (HD). Patients and Methods: Ninety­six patients with dyspeptic complaints were included in the study. They were divided into two groups; group one consisted of 46 patients with ESRD on HD and group two (control) of 50 patients without renal disease. All patients were subjected to upper gastrointestinal endoscopies, and gastric biopsies were obtained for histological evidence of H. pylori infection. Results: The mean age of both groups was similar. The prevalence of H.pylori among the two groups was not significantly different (45.7%Vs48%=p>0.05). The prevalence of duodenal ulcers was significantly higher in H.pylori positive than in H.pylori negative ESRD patients (p<0.05). GERD was significantly lower in H.pylori positive patients in both groups (p<0.001 and p<0.01 respectively). Conclusion: This study showed a similar prevalence of H.pylori infection in both groups. H.pylori infection in patients with ESRD is probably associated with increased risk of gastroduodenal lesions
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Omer El-Faroug El-Tinay, Salman Yousuf Guraya, Osman Noreldin
May-August 2004, 10(2):96-98
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Fibrolamellar hepatocellular carcinoma with alpha-one antitrypsin liver disease
Muneera Mohammed Al Bugami, Karim Louis Chaker Farahat, Hamad Ibrahim Al-Ashgar, Bo Hainau
May-August 2004, 10(2):92-95
  3,424 0 -
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